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Characterizing Adult Cochlear Supporting Cell Transcriptional Diversity Using Single-Cell RNA-Seq: Validation in the Adult Mouse and Translational Implications for the Adult Human Cochlea

Hearing loss is a problem that impacts a significant proportion of the adult population. Cochlear hair cell (HC) loss due to loud noise, chemotherapy and aging is the major underlying cause. A significant proportion of these individuals are dissatisfied with available treatment options which include...

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Détails bibliographiques
Publié dans:Front Mol Neurosci
Auteurs principaux: Hoa, Michael, Olszewski, Rafal, Li, Xiaoyi, Taukulis, Ian, Gu, Shoujun, DeTorres, Alvin, Lopez, Ivan A., Linthicum Jr., Fred H., Ishiyama, Akira, Martin, Daniel, Morell, Robert J., Kelley, Matthew W.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012811/
https://ncbi.nlm.nih.gov/pubmed/32116546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.00013
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