The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs

GPR88 is an orphan G protein-coupled receptor (GPCR) considered as a promising therapeutic target for neuropsychiatric disorders; its pharmacology, however, remains scarcely understood. Based on our previous report of increased delta opioid receptor activity in Gpr88 null mice, we investigated the i...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Laboute, Thibaut, Gandía, Jorge, Pellissier, Lucie P, Corde, Yannick, Rebeillard, Florian, Gallo, Maria, Gauthier, Christophe, Léauté, Audrey, Diaz, Jorge, Poupon, Anne, Kieffer, Brigitte L, Le Merrer, Julie, Becker, Jérôme AJ
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012601/
https://ncbi.nlm.nih.gov/pubmed/32003745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50519
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