Density, heterogeneity and deformability of red cells as markers of clinical severity in hereditary spherocytosis

Hereditary spherocytosis (HS) originates from defective anchoring of the cytoskeletal network to the transmembrane protein complexes of the red blood cell (RBC). Red cells in HS are characterized by membrane instability and reduced deformability and there is marked heterogeneity in disease severity...

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Publicado no:Haematologica
Main Authors: Huisjes, Rick, Makhro, Asya, Llaudet-Planas, Esther, Hertz, Laura, Petkova-Kirova, Polina, Verhagen, Liesbeth P., Pignatelli, Silvia, Rab, Minke A.E., Schiffelers, Raymond M., Seiler, Elena, van Solinge, Wouter W., Corrons, Joan-LLuis Vives, Kaestner, Lars, Mañú-Pereira, Maria, Bogdanov, Anna, van Wijk, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012482/
https://ncbi.nlm.nih.gov/pubmed/31147440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.188151
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