MYD88 mutations identify a molecular subgroup of diffuse large B-cell lymphoma with an unfavorable prognosis

The 2016 World Health Organization classification defines diffuse large B-cell lymphoma (DLBCL) subtypes based on Epstein-Barr virus (EBV) infection and oncogenic rearrangements of MYC/BCL2/BCL6 as drivers of lymphomagenesis. A subset of DLBCL, however, is characterized by activating mutations in MY...

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Publicat a:Haematologica
Autors principals: Vermaat, Joost S., Somers, Sebastiaan F., de Wreede, Liesbeth C., Kraan, Willem, de Groen, Ruben A.L., Schrader, Anne M. R., Kerver, Emile D., Scheepstra, Cornelis G., Berenschot, Henriëtte, Deenik, Wendy, Wegman, Jurgen, Broers, Rianne, de Boer, Jan-Paul D., Nijland, Marcel, van Wezel, Tom, Veelken, Hendrik, Spaargaren, Marcel, Cleven, Arjen H., Kersten, Marie José, Pals, Steven T.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012469/
https://ncbi.nlm.nih.gov/pubmed/31123031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.214122
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