Gene Ontology Causal Activity Modeling (GO-CAM) moves beyond GO annotations to structured descriptions of biological functions and systems

To increase the utility of Gene Ontology annotations for interpretation of genome-wide experimental data, we have developed GO-CAM, a structured framework for linking multiple GO annotations into an integrated model of a biological system. We expect that GO-CAM will enable new applications in pathwa...

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Veröffentlicht in:Nat Genet
Hauptverfasser: Thomas, Paul D., Hill, David P., Mi, Huaiyu, Osumi-Sutherland, David, Van Auken, Kimberly, Carbon, Seth, Balhoff, James P., Albou, Laurent-Philippe, Good, Benjamin, Gaudet, Pascale, Lewis, Suzanna E., Mungall, Christopher J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012280/
https://ncbi.nlm.nih.gov/pubmed/31548717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0500-1
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