GSK343 induces programmed cell death through the inhibition of EZH2 and FBP1 in osteosarcoma cells

Enhancer of zeste homolog 2 (EZH2) is an important member of the epigenetic regulatory factor polycomb group proteins (PcG) and is abnormally expressed in a wide variety of tumors, including osteosarcoma. Scientists consider EZH2 as an attractive target for the treatment of osteosarcoma and have fou...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Xiong, Xifeng, Zhang, Jinli, Li, Aiguo, Dai, Libing, Qin, Shengnan, Wang, Pengzhen, Liu, Wei, Zhang, Zhi, Li, Xiaojian, Liu, Zhihe
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012145/
https://ncbi.nlm.nih.gov/pubmed/31651209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2019.1680061
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