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Ibudilast attenuates peripheral inflammatory effects of methamphetamine in patients with methamphetamine use disorder

BACKGROUND: Preclinical studies suggest that the non-selective phosphodiesterase inhibitor, Ibudilast (IBUD) may contribute to the treatment of METH use disorder through the attenuation of METH-induced inflammatory markers such as adhesion molecules, sICAM-1 and sVCAM-1, and cytokines, IL-6 and TNF-...

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Detalhes bibliográficos
Publicado no:Drug Alcohol Depend
Main Authors: Li, Michael J., Briones, Marisa S., Heinzerling, Keith G., Kalmin, Mariah, Shoptaw, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012103/
https://ncbi.nlm.nih.gov/pubmed/31812878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2019.107776
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