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RNA imaging in living mice enabled by an in vivo hybridization chain reaction circuit with a tripartite DNA probe

RNA imaging in living animals helps decipher biology and creates new theranostics for disease treatment. Due to their low delivery efficiency and high background, however, fluorescence probes for in situ RNA imaging in living mice have not been reported. We develop a new cell-targeting fluorescent p...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Wu, Han, Chen, Ting-Ting, Wang, Xiang-Nan, Ke, Yonggang, Jiang, Jian-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012062/
https://ncbi.nlm.nih.gov/pubmed/32110357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03469b
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