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The effects of triptolide on the pharmacokinetics of sorafenib in rats and its potential mechanism

Context: Combining sorafenib with triptolide could inhibit tumour growth with greater efficacy than single-agent treatment. However, their herb–drug interaction remains unknown. Objective: This study investigates the herb–drug interaction between triptolide and sorafenib. Materials and methods: The...

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Publicat a:Pharm Biol
Autors principals: Wang, Xianming, Zhang, Xin, Liu, Fei, Wang, Minghai, Qin, Shiyong
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011964/
https://ncbi.nlm.nih.gov/pubmed/28614959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2017.1340963
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