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Caplacizumab in adult patients with acquired thrombotic thrombocytopenic purpura

Thrombotic thrombocytopenic purpura (TTP) is usually a fatal disease caused by a deficiency of the metalloproteinase, ADAMTS13, often due to autoimmunity. This leads to the development of pathogenic multimers of von Willebrand factor (vWF), causing an inappropriate interaction of platelets and vWF....

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Bibliografiske detaljer
Udgivet i:Ther Adv Hematol
Main Authors: Hanlon, Ashley, Metjian, Ara
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011322/
https://ncbi.nlm.nih.gov/pubmed/32095224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040620720902904
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