Pioglitazone attenuates advanced glycation end products‐induced apoptosis and calcification by modulating autophagy in tendon‐derived stem cells

Diabetes mellitus (DM) is one of the prominent risk factors for pathological development and progression of tendinopathy. One feature of DM‐related changes in tendinopathy is accumulation of advanced glycation end products (AGEs) in affected tendons. Pioglitazone (Pio), a peroxisome proliferator‐act...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Xu, Langhai, Xu, Kai, Wu, Zhipeng, Chen, Zhonggai, He, Yuzhe, Ma, Chiyuan, Moqbel, Safwat A. A., Ran, Jisheng, Zhang, Caihua, Wu, Lidong, Xiong, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011144/
https://ncbi.nlm.nih.gov/pubmed/31957239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14901
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