Prevalence and prognostic role of PIK3CA E545K mutation in Iranian colorectal cancer patients

AIM: This study aimed to evaluate the distribution of PIK3CA E545K mutation in Iranian CRC patients and explored its roles in disease prognosis. BACKGROUND: Deregulation of the phosphoinositide 3-kinase (PI3K) pathway contributes to the progression of tumors. The p110a (PIK3CA), a catalytic subunit...

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Bibliografski detalji
Izdano u:Gastroenterol Hepatol Bed Bench
Glavni autori: Ranjbar, Reza, Mohammadpour, Somayeh, Torshizi Esfahani, Amir, Namazian, Sina, Yaghob-Taleghani, Mohammad, Baghaei, Kaveh, Mortazavi Tabatabaei, Seyed Abdolreza, Pasharavesh, Leila, Nazemalhosseini-Mojarad, Ehsan
Format: Artigo
Jezik:Inglês
Izdano: Shaheed Beheshti University of Medical Sciences 2019
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011074/
https://ncbi.nlm.nih.gov/pubmed/32099598
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