Alpha-Glucosidase Inhibitors Alter Gut Microbiota and Ameliorate Collagen-Induced Arthritis

Acarose is an anti-diabetic drug and exhibits anti-arthritic effects. We hypothesized that acarbose influences the gut microbiota to affect the course of arthritis and tested this hypothesis in a collagen-induced arthritis (CIA) murine model. Acarbose in drinking water was administered via gastric g...

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Vydáno v:Front Pharmacol
Hlavní autoři: Zhang, Lingshu, Song, Pingfang, Zhang, Xiaowei, Metea, Christina, Schleisman, Matthew, Karstens, Lisa, Leung, Eric, Zhang, Jun, Xu, Qiang, Liu, Yi, Asquith, Mark, Chu, Cong-Qiu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010955/
https://ncbi.nlm.nih.gov/pubmed/32116681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01684
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