The Functional Effects of Key Driver KRAS Mutations on Gene Expression in Lung Cancer

Lung cancer is a common malignant cancer. Kirsten rat sarcoma oncogene (KRAS) mutations have been considered as a key driver for lung cancers. KRAS p.G12C mutations were most predominant in NSCLC which was comprised about 11–16% of lung adenocarcinomas (p.G12C accounts for 45–50% of mutant KRAS). Bu...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Zhang, Jisong, Hu, Huihui, Xu, Shan, Jiang, Hanliang, Zhu, Jihong, Qin, E., He, Zhengfu, Chen, Enguo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010953/
https://ncbi.nlm.nih.gov/pubmed/32117436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00017
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