Cellular dosimetry of [(177)Lu]Lu-DOTA-[Tyr(3)]octreotate radionuclide therapy: the impact of modeling assumptions on the correlation with in vitro cytotoxicity

BACKGROUND: Survival and linear-quadratic model fitting parameters implemented in treatment planning for targeted radionuclide therapy depend on accurate cellular dosimetry. Therefore, we have built a refined cellular dosimetry model for [(177)Lu]Lu-DOTA-[Tyr(3)]octreotate ((177)Lu-DOTATATE) in vitr...

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Vydáno v:EJNMMI Phys
Hlavní autoři: Tamborino, Giulia, De Saint-Hubert, Marijke, Struelens, Lara, Seoane, Dayana C., Ruigrok, Eline A. M., Aerts, An, van Cappellen, Wiggert A., de Jong, Marion, Konijnenberg, Mark W., Nonnekens, Julie
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010903/
https://ncbi.nlm.nih.gov/pubmed/32040783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40658-020-0276-5
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