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Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway

The diversity of the naïve T cell repertoire drives the replenishment potential and capacity of memory T cells to respond to immune challenges. Attrition of the immune system is associated with an increased prevalence of pathologies in aged individuals, but whether stem cell memory T lymphocytes (T(...

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Pubblicato in:Nat Commun
Autori principali: Kared, Hassen, Tan, Shu Wen, Lau, Mai Chan, Chevrier, Marion, Tan, Crystal, How, Wilson, Wong, Glenn, Strickland, Marie, Malleret, Benoit, Amoah, Amanda, Pilipow, Karolina, Zanon, Veronica, Govern, Naomi Mc, Lum, Josephine, Chen, Jin Miao, Lee, Bernett, Florian, Maria Carolina, Geiger, Hartmut, Ginhoux, Florent, Ruiz-Mateos, Ezequiel, Fulop, Tamas, Rajasuriar, Reena, Kamarulzaman, Adeeba, Ng, Tze Pin, Lugli, Enrico, Larbi, Anis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010798/
https://ncbi.nlm.nih.gov/pubmed/32041953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14442-6
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