Regulation of bone metabolism by megakaryocytes in a paracrine manner

Megakaryocytes (MKs) play key roles in regulating bone metabolism. To test the roles of MK-secreted factors, we investigated whether MK and promegakaryocyte (pro-MK) conditioned media (CM) may affect bone formation and resorption. K562 cell lines were differentiated into mature MKs. Mouse bone marro...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Lee, Young-Sun, Kwak, Mi Kyung, Moon, Sung-Ah, Choi, Young Jin, Baek, Ji Eun, Park, Suk Young, Kim, Beom-Jun, Lee, Seung Hun, Koh, Jung-Min
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010738/
https://ncbi.nlm.nih.gov/pubmed/32042021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59250-6
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