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Modeling the Effect of Temperature on Membrane Response of Light Stimulation in Optogenetically-Targeted Neurons

Optogenetics is revolutionizing Neuroscience, but an often neglected effect of light stimulation of the brain is the generation of heat. In extreme cases, light-generated heat kills neurons, but mild temperature changes alter neuronal function. To date, most in vivo experiments rely on light stimula...

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Veröffentlicht in:Front Comput Neurosci
Hauptverfasser: Peixoto, Helton M., Cruz, Rossana M. S., Moulin, Thiago C., Leão, Richardson N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010719/
https://ncbi.nlm.nih.gov/pubmed/32116619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncom.2020.00005
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