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Metformin reduces HGF-induced resistance to alectinib via the inhibition of Gab1
Alectinib is a second-generation anaplastic lymphoma kinase (ALK) inhibitor that has sufficient clinical efficacy and satisfactory safety in ALK-positive non-small cell lung cancer (NSCLC) patients with or without brain metastasis. Alectinib has now become an important drug in the first-line treatme...
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| Опубликовано в: : | Cell Death Dis |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7010683/ https://ncbi.nlm.nih.gov/pubmed/32041944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2307-5 |
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