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Melatonin controls microbiota in colitis by goblet cell differentiation and antimicrobial peptide production through Toll-like receptor 4 signalling

Microbial dysbiosis has long been postulated to be associated with the pathogenesis of inflammatory bowel disease (IBD). Although evidence supporting the anti-colitic effects of melatonin have been accumulating, it is not clear how melatonin affects the microbiota. Herein, we investigated the effect...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Kim, Seung Won, Kim, Soochan, Son, Mijeong, Cheon, Jae Hee, Park, Young Sook
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010660/
https://ncbi.nlm.nih.gov/pubmed/32042047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59314-7
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