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Rational Drug Design of Axl Tyrosine Kinase Type I Inhibitors as Promising Candidates Against Cancer

The high level of Axl tyrosine kinase expression in various cancer cell lines makes it an attractive target for the development of anti-cancer drugs. In this study, we carried out several sets of in silico screening for the ATP-competitive Axl kinase inhibitors based on different molecular docking p...

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Опубликовано в: :Front Chem
Главные авторы: Sarukhanyan, Edita, Shityakov, Sergey, Dandekar, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010640/
https://ncbi.nlm.nih.gov/pubmed/32117858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00920
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