Prioritizing Gene Cascading Paths to Model Colorectal Cancer Through Engineered Organoids

Engineered organoids by sequential introduction of key mutations could help modeling the dynamic cancer progression. However, it remains difficult to determine gene paths which were sufficient to capture cancer behaviors and to broadly explain cancer mechanisms. Here, as a case study of colorectal c...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Ping, Yanyan, Xu, Chaohan, Xu, Liwen, Liao, Gaoming, Zhou, Yao, Deng, Chunyu, Lan, Yujia, Yu, Fulong, Shi, Jian, Wang, Li, Xiao, Yun, Li, Xia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010597/
https://ncbi.nlm.nih.gov/pubmed/32117908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00012
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