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celsr1a is essential for tissue homeostasis and onset of aging phenotypes in the zebrafish

The use of genetics has been invaluable in defining the complex mechanisms of aging and longevity. Zebrafish, while a prominent model for vertebrate development, have not been used systematically to address questions of how and why we age. In a mutagenesis screen focusing on late developmental pheno...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Li, Chunmei, Barton, Carrie, Henke, Katrin, Daane, Jake, Treaster, Stephen, Caetano-Lopes, Joana, Tanguay, Robyn L, Harris, Matthew P
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010407/
https://ncbi.nlm.nih.gov/pubmed/31985398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50523
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