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Structure of the AAVhu.37 capsid by cryoelectron microscopy

Adeno-associated viruses (AAVs) are used as in vivo gene-delivery vectors in gene-therapy products and have been heavily investigated for numerous indications. Over 100 naturally occurring AAV serotypes and variants have been isolated from primate samples. Many reports have described unique properti...

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Veröffentlicht in:Acta Crystallogr F Struct Biol Commun
Hauptverfasser: Kaelber, Jason T., Yost, Samantha A., Webber, Keith A., Firlar, Emre, Liu, Ye, Danos, Olivier, Mercer, Andrew C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010358/
https://ncbi.nlm.nih.gov/pubmed/32039886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X20000308
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