Identification of Plasmodium falciparum circumsporozoite protein-specific CD8+ T cell epitopes in a malaria exposed population

BACKGROUND: Sterile protection against malaria, most likely mediated by parasite-specific CD8+ T cells, has been achieved by attenuated sporozoite vaccination of animals as well as malaria-naïve and malaria-exposed subjects. The circumsporozoite protein (CSP)-based vaccine, RTS,S, shows low efficacy...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kusi, Kwadwo A., Aggor, Felix E., Amoah, Linda E., Anum, Dorothy, Nartey, Yvonne, Amoako-Sakyi, Daniel, Obiri-Yeboah, Dorcas, Hollingdale, Michael, Ganeshan, Harini, Belmonte, Maria, Peters, Bjoern, Kim, Yohan, Tetteh, John, Kyei-Baafour, Eric, Dodoo, Daniel, Villasante, Eileen, Sedegah, Martha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7010280/
https://ncbi.nlm.nih.gov/pubmed/32040522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228177
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