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Downregulation of MiR-218-5p Protects Against Oxygen-Glucose Deprivation/Reperfusion-Induced Injuries of PC12 Cells via Upregulating N-myc Downstream Regulated Gene 4 (NDRG4)

BACKGROUND: Cerebral ischemia is a major player of acute ischemic stroke (AIS) and mainly caused by blood vessels obstruction-induced reduced blood flow. Furthermore, miR-218-5p level was elevated in patients with AIS compared with controls. The present study investigated the biochemical mechanisms...

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Bibliografiske detaljer
Udgivet i:Med Sci Monit
Main Authors: Zhu, Huiying, Wang, Xiaojing, Chen, Shaoyuan
Format: Artigo
Sprog:Inglês
Udgivet: International Scientific Literature, Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7009718/
https://ncbi.nlm.nih.gov/pubmed/32048632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.920101
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