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Electrical recognition of the twenty proteinogenic amino acids using an aerolysin nanopore

Efforts to sequence single protein molecules in nanopores(1–5) have been hampered by the insufficient sensitivity of a conventional nanopore measurement for identification of the few atom differences among the amino acids. Here we report ionic current detection of all twenty proteinogenic amino acid...

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Detalles Bibliográficos
Publicado en:Nat Biotechnol
Main Authors: Ouldali, Hadjer, Sarthak, Kumar, Ensslen, Tobias, Piguet, Fabien, Manivet, Philippe, Pelta, Juan, Behrends, Jan C., Aksimentiev, Aleksei, Oukhaled, Abdelghani
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008938/
https://ncbi.nlm.nih.gov/pubmed/31844293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0345-2
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