Identification of 67 Pleiotropic Genes Associated With Seven Autoimmune/Autoinflammatory Diseases Using Multivariate Statistical Analysis

Although genome-wide association studies (GWAS) have a dramatic impact on susceptibility locus discovery, this univariate approach has limitations in detecting complex genotype-phenotype correlations. Multivariate analysis is essential to identify shared genetic risk factors acting through common bi...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Jia, Xiaocan, Shi, Nian, Feng, Yu, Li, Yifan, Tan, Jiebing, Xu, Fei, Wang, Wei, Sun, Changqing, Deng, Hongwen, Yang, Yongli, Shi, Xuezhong
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008725/
https://ncbi.nlm.nih.gov/pubmed/32117227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00030
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