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Molecular Surveillance for Polymorphisms Associated with Artemisinin-Based Combination Therapy Resistance in Plasmodium falciparum Isolates Collected in the State of Roraima, Brazil

Given that the C580Y polymorphism in the Plasmodium falciparum propeller domain of the kelch 13 gene (pfk13) was documented in Guyana, monitoring for mutations associated with antimalarial resistance was undertaken in neighboring Roraima state in Brazil. Polymorphisms in the pfmdr1 and pfk13 genes w...

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Publicado en:Am J Trop Med Hyg
Autores principales: Lucchi, Naomi W., Abdallah, Rispah, Louzada, Jaime, Udhayakumar, Venkatachalam, Oliveira-Ferreira, Joseli
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society of Tropical Medicine and Hygiene 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008347/
https://ncbi.nlm.nih.gov/pubmed/31833470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.19-0749
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