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Layer-by-layer pH-sensitive nanoparticles for drug delivery and controlled release with improved therapeutic efficacy in vivo

In this work, a pH-sensitive liposome–polymer nanoparticle (NP) composed of lipid, hyaluronic acid (HA) and poly(β-amino ester) (PBAE) was prepared using layer-by-layer (LbL) method for doxorubicin (DOX) targeted delivery and controlled release to enhance the cancer treatment efficacy. The NP with p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Deliv
Hauptverfasser: Men, Wanfu, Zhu, Peiyao, Dong, Siyuan, Liu, Wenke, Zhou, Kun, Bai, Yu, Liu, Xiangli, Gong, Shulei, Zhang, Shuguang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7008239/
https://ncbi.nlm.nih.gov/pubmed/31924103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1709922
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