The LC3-Conjugation Machinery Specifies the Loading of RNA-Binding Proteins into Extracellular Vesicles

Traditionally viewed as an autodigestive pathway, autophagy also facilitates cellular secretion; however, the mechanisms underlying these processes remain unclear. Here, we demonstrate that components of the autophagy machinery specify secretion within extracellular vesicles (EVs). Using a proximity...

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Udgivet i:Nat Cell Biol
Main Authors: Leidal, Andrew M., Huang, Hector H., Marsh, Timothy, Solvik, Tina, Zhang, Dachuan, Ye, Jordan, Kai, FuiBoon, Goldsmith, Juliet, Liu, Jennifer Y., Huang, Yu-Hsin, Monkkonen, Teresa, Vlahakis, Ariadne, Huang, Eric J., Goodarzi, Hani, Yu, Li, Wiita, Arun P., Debnath, Jayanta
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007875/
https://ncbi.nlm.nih.gov/pubmed/31932738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0450-y
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