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The SUMO ligase Su(var)2-10 controls eu- and heterochromatic gene expression via establishment of H3K9 trimethylation and negative feedback regulation

Chromatin is critical for genome compaction and gene expression. On a coarse scale, the genome is divided into euchromatin, which harbors the majority of genes and is enriched in active chromatin marks, and heterochromatin, which is gene-poor but repeat-rich. The conserved molecular hallmark of hete...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Ninova, Maria, Godneeva, Baira, Chen, Yung-Chia Ariel, Luo, Yicheng, Prakash, Sharan J., Jankovics, Ferenc, Erdélyi, Miklós, Aravin, Alexei A., Tóth, Katalin Fejes
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007874/
https://ncbi.nlm.nih.gov/pubmed/31901448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.09.033
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