Lisa: inferring transcriptional regulators through integrative modeling of public chromatin accessibility and ChIP-seq data

We developed Lisa (http://lisa.cistrome.org/) to predict the transcriptional regulators (TRs) of differentially expressed or co-expressed gene sets. Based on the input gene sets, Lisa first uses histone mark ChIP-seq and chromatin accessibility profiles to construct a chromatin model related to the...

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Publicat a:Genome Biol
Autors principals: Qin, Qian, Fan, Jingyu, Zheng, Rongbin, Wan, Changxin, Mei, Shenglin, Wu, Qiu, Sun, Hanfei, Brown, Myles, Zhang, Jing, Meyer, Clifford A., Liu, X. Shirley
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007693/
https://ncbi.nlm.nih.gov/pubmed/32033573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-1934-6
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