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Near-infrared optogenetic engineering of photothermal nanoCRISPR for programmable genome editing

We herein report an optogenetically activatable CRISPR-Cas9 nanosystem for programmable genome editing in the second near-infrared (NIR-II) optical window. The nanosystem, termed nanoCRISPR, is composed of a cationic polymer-coated Au nanorod (APC) and Cas9 plasmid driven by a heat-inducible promote...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Chen, Xiaohong, Chen, Yuxuan, Xin, Huhu, Wan, Tao, Ping, Yuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007568/
https://ncbi.nlm.nih.gov/pubmed/31941712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912220117
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