Acrosin is essential for sperm penetration through the zona pellucida in hamsters

During natural fertilization, mammalian spermatozoa must pass through the zona pellucida before reaching the plasma membrane of the oocyte. It is assumed that this step involves partial lysis of the zona by sperm acrosomal enzymes, but there has been no unequivocal evidence to support this view. Her...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Hirose, Michiko, Honda, Arata, Fulka, Helena, Tamura-Nakano, Miwa, Matoba, Shogo, Tomishima, Toshiko, Mochida, Keiji, Hasegawa, Ayumi, Nagashima, Kiyoshi, Inoue, Kimiko, Ohtsuka, Masato, Baba, Tadashi, Yanagimachi, Ryuzo, Ogura, Atsuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007544/
https://ncbi.nlm.nih.gov/pubmed/31964830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917595117
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