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Time-dependent effects of histone deacetylase inhibition in sepsis-associated acute kidney injury

BACKGROUND: Sepsis, a dysregulated host response to infection with results in organ dysfunction, has been a major challenge to the development of effective therapeutics. Sepsis-associated acute kidney injury (S-AKI) results in a 3–5-fold increase in the risk of hospital mortality compared to sepsis...

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Detalhes bibliográficos
Publicado no:Intensive Care Med Exp
Main Authors: Wen, Xiaoyan, Li, Shengnan, Frank, Alicia, Chen, Xiukai, Emlet, David, Hukriede, Neil A., Kellum, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007462/
https://ncbi.nlm.nih.gov/pubmed/32034542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-020-0297-3
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