Tetrahydrobenzimidazole TMQ0153 triggers apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia

By comparing imatinib-sensitive and -resistant chronic myeloid leukemia (CML) cell models, we investigated the molecular mechanisms by which tetrahydrobenzimidazole derivative TMQ0153 triggered caspase-dependent apoptosis at low concentrations accompanied by loss of mitochondrial membrane potential...

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Song, Sungmi, Lee, Jin-Young, Ermolenko, Ludmila, Mazumder, Aloran, Ji, Seungwon, Ryu, Heeju, Kim, HyeJin, Kim, Dong-Wook, Lee, Jung Weon, Dicato, Mario, Christov, Christo, Schnekenburger, Michael, Cerella, Claudia, Gérard, Déborah, Orlikova-Boyer, Barbora, Al-Mourabit, Ali, Diederich, Marc
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007439/
https://ncbi.nlm.nih.gov/pubmed/32034134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2304-8
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