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Genomic and phenotypic analyses of six offspring of a genome-edited hornless bull

Genome editing followed by reproductive cloning was previously used to produce two hornless dairy bulls. We crossed one genome-edited dairy bull, homozygous for the dominant P(C) Celtic POLLED allele, with horned cows (pp) and obtained six heterozygous (P(C)p) polled calves. The calves had no horns...

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Publicado en:Nat Biotechnol
Main Authors: Young, Amy E., Mansour, Tamer A., McNabb, Bret R., Owen, Joseph R., Trott, Josephine F., Brown, C. Titus, Van Eenennaam, Alison L.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group US 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007412/
https://ncbi.nlm.nih.gov/pubmed/31591551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-019-0266-0
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