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Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas
BACKGROUND: Uterine and ovarian carcinosarcomas (CS) are rare cancers with poor prognosis. Sacituzumab-govitecan (SG) is a new class of antibody-drug-conjugate (ADC) targeting the human-trophoblast-cell-surface marker (Trop-2) conjugated with the active metabolite of irinotecan (SN-38). We evaluated...
Kaydedildi:
| Yayımlandı: | Oncotarget |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Impact Journals LLC
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7007291/ https://ncbi.nlm.nih.gov/pubmed/32082489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27342 |
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