NSABP B-47/NRG Oncology Phase III Randomized Trial Comparing Adjuvant Chemotherapy With or Without Trastuzumab in High-Risk Invasive Breast Cancer Negative for HER2 by FISH and With IHC 1+ or 2+

PURPOSE: Adjuvant trastuzumab reduces invasive breast cancer (IBC) recurrence and risk for death in patients with HER2-amplified or overexpressing IBC. A subset of patients in the landmark trastuzumab adjuvant trials who originally tested HER2-positive but were HER2-negative by central HER2 testing...

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Опубликовано в: :J Clin Oncol
Главные авторы: Fehrenbacher, Louis, Cecchini, Reena S., Geyer Jr, Charles E., Rastogi, Priya, Costantino, Joseph P., Atkins, James N., Crown, John P., Polikoff, Jonathan, Boileau, Jean-Francois, Provencher, Louise, Stokoe, Christopher, Moore, Timothy D., Robidoux, André, Flynn, Patrick J., Borges, Virginia F., Albain, Kathy S., Swain, Sandra M., Paik, Soonmyung, Mamounas, Eleftherios P., Wolmark, Norman
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Clinical Oncology 2020
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ORIGINAL REPORTS
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007289/
https://ncbi.nlm.nih.gov/pubmed/31821109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.01455
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