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Automated High-Throughput Capillary Circular Dichroism and Intrinsic Fluorescence Spectroscopy for Rapid Determination of Protein Structure

[Image: see text] Assessing the physical stability of proteins is one of the most important challenges in the development, manufacture, and formulation of biotherapeutics. Here, we describe a method for combining and automating circular dichroism and intrinsic protein fluorescence spectroscopy. By r...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Moore-Kelly, Charles, Welsh, John, Rodger, Alison, Dafforn, Tim R., Thomas, Owen R. T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006967/
https://ncbi.nlm.nih.gov/pubmed/31584804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b03259
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