Elucidating the mechanism of action of alpha-1-antitrypsin using retinal pigment epithelium cells exposed to high glucose. Potential use in diabetic retinopathy

BACKGROUND: Alpha-1-antitrypsin is a protein involved in avoidance of different processes that are seen in diabetic retinopathy pathogenesis. These processes include apoptosis, extracellular matrix remodeling and damage of vessel walls and capillaries. Furthermore, because of its anti-inflammatory e...

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Publicat a:PLoS One
Autors principals: Potilinski, María Constanza, Ortíz, Gustavo A., Salica, Juan P., López, Emiliano S., Fernández Acquier, Mariano, Chuluyan, Eduardo, Gallo, Juan E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006930/
https://ncbi.nlm.nih.gov/pubmed/32032388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228895
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