Hypertensive Rats Treated Chronically With N(ω)-Nitro-L-Arginine Methyl Ester (L-NAME) Induced Disorder of Hepatic Fatty Acid Metabolism and Intestinal Pathophysiology

N(ω)-nitro-L-arginine methyl ester (L-NAME), an inhibitor of nitric oxide (NO) biosynthesis, results in hypertension and liver injury. This study aimed at investigating the changes of liver lipometabonomics and exploring the underlying mechanisms of liver injury in the L-NAME-treated rats. The male...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Li, Bo, He, Xinglishang, Lei, Shan-Shan, Zhou, Fu-Chen, Zhang, Ning-Yu, Chen, Ye-Hui, Wang, Yu-Zhi, Su, Jie, Yu, Jing-Jing, Li, Lin-Zi, Zheng, Xiang, Luo, Rong, Kołodyńska, Dorota, Xiong, Shan, Lv, Gui-Yuan, Chen, Su-Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006817/
https://ncbi.nlm.nih.gov/pubmed/32076406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01677
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