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Mechanical instability induces osteoclast differentiation independent of the presence of a fibrous tissue interface and osteocyte apoptosis in a rat model for aseptic loosening

Background and purpose — Insufficient initial fixation or early micromotion of an implant is associated with a thin layer of fibrous tissue at the peri-implant interface. It is unknown if bone loss is induced by the fibrous tissue interface acting as an active biological membrane, or as a membrane t...

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Detalhes bibliográficos
Publicado no:Acta Orthop
Main Authors: Madsen, Rune Vinther, Nam, Denis, Schilcher, Jörg, Dvorzhinskiy, Aleksey, Sutherland, James P, Bostrom, F Mathias, Fahlgren, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006729/
https://ncbi.nlm.nih.gov/pubmed/31762353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17453674.2019.1695351
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