B Cell Receptor Immunogenetics in B Cell Lymphomas: Immunoglobulin Genes as Key to Ontogeny and Clinical Decision Making

The clonotypic B cell receptor immunoglobulin (BcR IG) plays a seminal role in B cell lymphoma development and evolution. From a clinical perspective, this view is supported by the remarkable therapeutic efficacy of BcR signaling inhibitors, even among heavily pre-treated, relapsed/refractory patien...

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Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Gemenetzi, Katerina, Agathangelidis, Andreas, Zaragoza-Infante, Laura, Sofou, Electra, Papaioannou, Maria, Chatzidimitriou, Anastasia, Stamatopoulos, Kostas
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Oncology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006488/
https://ncbi.nlm.nih.gov/pubmed/32083012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00067
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