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A Phase II Clinical Trial of Ixabepilone (Ixempra®, BMS-247550, NSC 710428), an Epothilone B Analog, in Patients with Metastatic Renal Cell Carcinoma

PURPOSE: Ixabepilone (Ixempra®; BMS-247550) is an epothilone B analog and non-taxane microtubule-stabilizing compound with clinical activity in a range of solid tumors. This phase II study was conducted to assess the efficacy and safety of ixabepilone in patients with metastatic renal cell carcinoma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Huang, Hui, Menefee, Michael, Edgerly, Maureen, Zhuang, Sen, Kotz, Herb, Poruchynsky, Marianne, Huff, Lyn Mickley, Bates, Susan, Fojo, Tito
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006234/
https://ncbi.nlm.nih.gov/pubmed/20179242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-0379
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