Pharmacological conditioning for juvenile idiopathic arthritis: a potential solution to reduce methotrexate intolerance

BACKGROUND: Methotrexate (MTX) therapy has proven to be a successful and safe treatment for Juvenile Idiopathic Arthritis (JIA). Despite the high efficacy rates of MTX, treatment outcomes are often complicated by burdensome gastro-intestinal side effects. Intolerance rates for MTX in children are hi...

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Detalhes bibliográficos
Publicado no:Pediatr Rheumatol Online J
Main Authors: Smits, Rosanne M., Veldhuijzen, Dieuwke S., van Middendorp, Henriet, Hissink Muller, Petra C. E., Armbrust, Wineke, Legger, Elizabeth, Wulffraat, Nico M., Evers, Andrea W. M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Hypothesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006148/
https://ncbi.nlm.nih.gov/pubmed/32033577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12969-020-0407-5
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