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Extracellular vesicles originating from glioblastoma cells increase metalloproteinase release by astrocytes: the role of CD147 (EMMPRIN) and ionizing radiation

BACKGROUND: Glioblastoma multiforme is an aggressive primary brain tumor that is characterized by local invasive growth and resistance to therapy. The role of the microenvironment in glioblastoma invasiveness remains unclear. While carcinomas release CD147, a protein that signals for increased matri...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Colangelo, Nicholas W., Azzam, Edouard I.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006136/
https://ncbi.nlm.nih.gov/pubmed/32033611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0494-4
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