Rectification of radiotherapy-induced cognitive impairments in aged mice by reconstituted Sca-1(+) stem cells from young donors

BACKGROUND: Radiotherapy is widely used and effective for treating brain tumours, but inevitably impairs cognition as it arrests cellular processes important for learning and memory. This is particularly evident in the aged brain with limited regenerative capacity, where radiation produces irreparab...

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Veröffentlicht in:J Neuroinflammation
Hauptverfasser: Wlodarek, Lukasz, Cao, Feng, Alibhai, Faisal J., Fekete, Adam, Noyan, Nima, Tobin, Stephanie W., Marvasti, Tina B., Wu, Jun, Li, Shu-Hong, Weisel, Richard D., Wang, Lu-Yang, Jia, Zhengping, Li, Ren-Ke
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006105/
https://ncbi.nlm.nih.gov/pubmed/32028989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1681-3
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