MiR-612 regulates invadopodia of hepatocellular carcinoma by HADHA-mediated lipid reprogramming

BACKGROUND: MicroRNA-612 (miR-612) has been proven to suppress EMT, stemness, and tumor metastasis of hepatocellular carcinoma (HCC) via PI3K/AKT2 and Sp1/Nanog signaling. However, its biological roles on HCC progression are far from elucidated. METHODS: We found direct downstream target of miR-612,...

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Vydáno v:J Hematol Oncol
Hlavní autoři: Liu, Yang, Lu, Li-Li, Wen, Duo, Liu, Dong-Li, Dong, Li-Li, Gao, Dong-Mei, Bian, Xin-Yu, Zhou, Jian, Fan, Jia, Wu, Wei-Zhong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006096/
https://ncbi.nlm.nih.gov/pubmed/32033570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0841-3
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